Theme: Exploring the Facets of Sequencing & Bio-Statistics

NGS Congress 2018

NGS Congress 2018

Conferences Series LLC invites all the participants from everywhere the globe to attend the “International Conference on Next Generation Sequencing and Biostatics” throughout October 17-18, 2018 at Dubai, UAE which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions.

NGS Congress 2018  could be a multidisciplinary field with analysis interests covering all aspects of recent molecular and cellular organic chemistry. NGS Congress 2018 is usually thought of as a tool to research and to check biology. It deals with the structure, operate and interactions amongst biological macromolecules.

The theme of the conference "Exploring the facets of Sequencing and Biostatistics", can specialize in the study of the molecular mechanisms by that genetic information present on deoxyribonucleic acid is in a position to lead to the processes of life. NGS Congress 2018  has its applications in varied fields. The findings of biochemistry are applied primarily in medicine, nutrition, and agriculture. In medicine, biochemists investigate the cause and cure for the malady. In nutrition, it results in maintain health and effects of deficiency of nutrients. In agriculture, biochemists investigate soil and fertilizers, and try to get ways to improve crop cultivation, storage and cuss management.

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Track 1. Next Generation Sequencing:

Next-generation sequencing (NGS), is   also known as high-throughput sequencing, is the catch-all method used to describe a number of different modern sequencing technologies including: Illumina sequencing. Roche 454 sequencing. Ion torrent: Proton / PGM sequencing. Solid sequencing. The latest advances in next-generation sequencing methods are revolutionizing the way biological research is conducted.

Track 2. Sequencing:

Sequencing is helped to determine the primary structure   of an unbranched biopolymer. Sequencing results in a symbolic linear depiction known as a sequence which succinctly summarizes much of the atomic-level structure of the sequenced molecule. DNA sequencing is helps in determining the nucleotide order of a given DNA fragment. So far, most DNA sequencing has been performed using the chain termination method developed by Frederick Sanger.

The sequence of DNA encodes the necessary information for living things to survive and reproduce. Determining the sequence is therefore useful in fundamental research into why and how organisms live, as well as in applied subjects. Because of the basic importance DNA has   to living things, knowledge of DNA sequences is useful in any area of biological research.

Track 3.  DNA Sequencing:

DNA sequencing is the method of deciding the precise order of nucleotides within a DNA molecule. It contains any method or technology that is used to determine the order of the four bases -adenine, guanine, cytosine, and thymine -in a strand of DNA. The DNA sequencing methods have greatly accelerated biological and medical research and discovery.

This technology   has become essential   for fundamental biological research, and in many applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematic.

Track 4. RNA Sequencing:

RNA-Sequence is   also called as whole transcriptome shotgun sequencing(WTSS), uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment in time.

This technique is used to analyze the continually changing cellular transcriptome. Specifically, RNA-Sequence  facilitates the ability to look at alternative gene spliced transcripts, post-transcriptional modifications, gene fusion, mutations/SNPs and changes in gene expression over time, or differences in gene expression in different groups or treatments.

In addition to mRNA transcripts, RNA-Sequence can look at different populations of RNA to include total RNA, small RNA, such as miRNA, tRNA, and ribosomal profiling. RNA-Sequence can also be used to determine exon/intron boundaries and verify or amend previously annotated 5' and 3' gene boundaries.

Prior to RNA-Sequence, gene expression studies were done with hybridization-based microarrays. Issues with microarrays include cross-hybridization artifacts, poor quantification of lowly and highly expressed genes, and needing to know the sequence a priori. Because of these technical issues, transcriptomics transmitted   to sequencing-based methods. These progressed from Sanger sequencing of Expressed Sequence Tag libraries, to chemical tag-based methods and finally to the current technology, next-generation sequencing of cDNA.

 

Track 5.  Protein Sequencing:

Protein sequencing is the process of determining the amino acid sequence of all or part of a protein or peptide. This may serve to identify the protein or characterize its post-translational modifications. The two different methods of protein sequencing are   Mass spectrometry and Edman degradation using a protein sequenator. Mass spectrometry methods are presently the most popularly used for protein sequencing and for recognition. Protein sequencing is mainly depending on chemical or enzymatic digestion techniques to separate peptides and detect the amount and composition of amino acid residue. protein sequencing services supplies accurate and reliable protein characterization and identification.

Mass spectrometry of peptides by enzymatic digest is a common technique of protein identification, Edman sequencing also known as automated Gas Phase Sequencing (GPS) supplies additional data which is inaccessible via mass spectrometry methods. GPS is used to identify unknown proteins as well as to check the quality of recombinant proteins and determine enzyme cleavage sites. It is a powerful complimentary technique used throughout all stages of drug discovery.

Track 6.  Illumina Sequencing:

Illumina sequencing is a technique used to determine the series of base pairs in DNA, also known as DNA sequencing. The reversible terminated chemistry concept was invented by Bruno Canard and Simon sarfati at the Pasteur Institute in Paris. Illumina sequencing technique works in three basic steps -  amplify, sequence, and analyze. The process begins with purified DNA. The   process begins with purified DNA.

Track 7. Sequence Alignment:

Sequence alignment is the method of ordering   the sequences of DNA, RNA, or protein to recognize regions because of resemblance that may be a consequence of functional, structural, evolutionary relationships between the sequences. Aligned sequences of nucleotide or amino acid residues are typically represented as rows within a matrix. This technology is also used for non-biological sequences, such as calculating the edit distance cost between strings in a natural language or in financial data.

Track 8. Sequencing Services:

As the largest gene synthesis and comprehensive molecular biology service provider in the USA with proven capability and reliability, Genscript now expands DNA sequencing services in North America to offer customers high speed and superior quality services. The Sanger DNA sequencing services are performed by professionally trained staff on state-of-the-art instrument and analyzed with advanced bioinformatics tools.

Track 9.  Clinical Bio-Statistics:

Clinical Biostatistics: It encompasses the statistical strategies which are accustomed to govern uncertainties   in the field of medicine and health. It comprehends biostatistics in clinical research and clinical trials, biostatistics research and methodology, clinical decision making, statistical methods in diagnostic drugs, statistical and computing methods.

Track 10. Statistical Method:

Statistical Methods: It includes strategies which are utilized as a part of biostatistics and computing. It incorporates points such as vigorous techniques in biostatistics, longitudinal studies, analysis with deficient data, meta-analysis, Monte-Carlo strategies, quantitative issues in health-risk analysis, statistical methodologies in genetic studies, ecological statistics and biostatistical routines in epidemiology.

Track 11. Bayesian Statistics:

Bayesian statistics: It is a subset of the sphere of statistics during which the proof about the concerning verity of the world is expressed in terms of degrees of belief or, ma lot specifically, Bayesian probabilities. It includes of varies approaches like Bayesian inference, stochastic structural improvement and Bayesian statistics, semi-parametric Bayesian analysis, Bayesian multiple modification point analysis, infrared spectroscopic analysis with Bayesian statistics and Bayesian dynamic models.

Track 12. Computational Systems Biology:

Computational Systems Biology: Systems biology is the investigation of frameworks of biological components, which might be atoms, molecules, cells, life forms or whole species. Living systems are dynamic and complex and their conduct might be difficult to anticipate from the properties of individual parts. In these days computer science assumes an imperative part in concentrating on the system biology. This track incorporates different themes like biostatistics in systems biology, machine learning and artificial intelligence, information analysis.

Track 13. Regression Analysis:

Regression Analysis: In statistics study, regression analysis has been statistical process for estimating the relationships among variables. It includes several techniques for modelling and analyzing many variables, once the main focus is on the link between a dependent variable and one or a lot of freelance variables. This track contains numerous sub topics like linear and non-linear analysis, variance and regression analysis, statistical methods for categorical data analysis, multiple regression with categorical information and biostatistical analysis software.

Track 14. Bio-Statistics Application:

Biostatistics is the study of science that deals with the statistical methods for describing and comparing the phenomenon of particular subject which helps in managing medical uncertainties. Its applications are wide spread in medicine, health, biology etc. for interpretation of data based on observations and facts.

Conferenceseries.com proudly announce “ International Conference on Next Generation Sequencing and Biostatics” which will be held during October 17-18 2018,Dubai,UAE.We organize 1000+ Global Events every year in Conference series, on Clinical, Medicine, Pharma and Science & Technology every year across USA, Europe, Asia, Middle East, Australia and UK with support from 1000 more scientific societies and publishes 700+ open access journals  which contains over 100000 eminent personalities, reputed scientists as editorial board and organizing committee members.

NGS Congress 2018 is a multidisciplinary field with research interests covering all aspects of modern molecular and cellular biochemistry. Biochemistry is often considered as a tool to investigate and to study molecular biology. It deals with the structure, function and interactions amongst biological macromolecules.

The theme of the conference "Exploring the facets of Biostatistics and Sequencing", will focus on the study of the molecular mechanisms by which genetic information present on DNA is able to result in the processes of life. Biochemistry has its applications in various fields. The findings of biochemistry are applied primarily in medicine, nutrition, and agriculture. In medicine, biochemists investigate the cause and cure for the disease. In nutrition, it leads to maintain health and effects of deficiency of nutrients. In agriculture, biochemists investigate soil and fertilizers, and try to discover ways to improve crop cultivation, storage and pest control.

Why to attend?

NGS Congress 2018  is a vast emerging discipline that uses genetic information from an individual as part of their clinical diagnostic care (e.g., for diagnostic or therapeutic decision-making) and the health outcomes and policy implications from that clinical use. NGS Congress 2018 provides a platform where you can meet top notch experts in the field and molecular biology to discuss molecular mechanisms by which genetic information encoded in DNA. 

NGS Congress 2018 mainly focusses on the universities, institutes, research centers and major societies along with companies which hold a big market in laboratory technologies. Target audience involves students, faculties, researchers, scientists, dean, directors and CEO's of the companies.

We welcome all interested participants to join us for our conference on Biochemistry at the exquisite destination of  Dubai,UAE.

Our Conference will provide a perfect platform to enlighten knowledge through:

· Innovative talks by the experts of the global scientific community

· Sterling workshop and sessions

· Remarkable Awards and Global Recognition to meritorious Researchers

· Global Networking with 50+ Countries across the globe

· Novel Techniques to Benefit Your Research

· Global Business and Networking Opportunities

· Exquisite Platform for showcasing your products and International Sponsorship

About Dubai,UAE:

Dubai is situated on the Eastern shore of the Arabian Peninsula, in the south west corner of the Arabian Gulf. It is greatly outstanding for its warm friendliness and rich social legacy, and the Emirati individuals are inviting and liberal in their way to deal with guests. With year-round daylight, charming deserts, wonderful shorelines, extravagant lodgings and shopping centres, entrancing legacy attractions and a flourishing business group, Dubai gets a great many relaxation and business guests every year from around the globe. The nearby money is the dirham, which is pegged at AED 3.67 to 1 US dollar. Dubai is tolerant and cosmopolitan and all guests are welcome. Be that as it may, Islam is a lifestyle in the city, and in this manner visitors ought to receive a specific level of social and religious affectability for the length of their remain. Dubai is a city and emirate in the United Arab Emirates known for extravagance shopping, ultramodern engineering and a vivacious nightlife scene. Burj Khalifa, an 830m-tall tower, commands the high rise filled horizon. At its foot lies Dubai Fountain, with planes and lights choreographed to music. On manufactured islands simply seaward is Atlantis, The Palm, a resort with water and marine-creature parks.

Dubai is a goal that blends current culture with history, experience with world-class shopping and amusement. Get a show at the Dubai Opera, see downtown from on the Burj Khalifa and spend an evening along Dubai Creek investigating the gold, material and flavour souks. In case you're searching for rushes, you can coast over the leave rises in a hot air swell, move on board a fast ride at IMG Worlds of Adventure or skydive over the Palm Jumeirah.

 

Scope and Importance of Next Generation Sequencing Research

• DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule. Next Generation Sequencing  technique is to identify and to understand the importance of genetic variation in clinical testing. Using NGS technique  an entire human genome can be sequenced  within a single day. In contrast previously, it used to take decades to decipher the final draft of human genomes.

Importance of NGS in Clinical practice:

• NGS captures a broader spectrum of mutations than Sanger sequencing.
• Genomes can be interrogated without bias. NGS is completely unselective and used to interrogate full genomes or exomes to discover entirely novel mutations and disease causing genes.
• NGS employed for very sensitive investigations such as interrogating foetal DNA from maternal blood or tracking the levels of tumour cells from the circulation of cancer patients.
• Market segments that provide exceptional growth opportunities include cancer, rare genetic diseases and reproductive health.
• The HGP led to significant improvements in the efficiency and costs of DNA sequencing.
• Beginning in 2005, the launch of next-generation sequencing technologies radically changed the structure of the industry and opened up exciting new market applications.
• The costs of sequencing have rapidly reduced to the point where it is now feasible for complex NGS tests to be priced in the range of other multiplex genetic tests.
• The NGS clinical market is beginning to establish a foothold in the molecular diagnostic industry and holds great commercial promise.
• More than 85 clinical laboratories are now offering NGS-based testing services.

Why Dubai?

  • Dubai is situated on the Eastern shore of the Arabian Peninsula, in the south west corner of the Arabian Gulf.
  • It is greatly outstanding for its warm friendliness and rich social legacy, and the Emirati individuals are inviting and liberal in their way to deal with guests.
  • With year-round daylight, charming deserts, wonderful shorelines, extravagant lodgings and shopping centres, entrancing legacy attractions and a flourishing business group, Dubai gets a great many relaxation and business guests every year from around the globe.
  • The nearby money is the dirham, which is pegged at AED 3.67 to 1 US dollar. Dubai is tolerant and cosmopolitan and all guests are welcome. Be that as it may, Islam is a lifestyle in the city, and in this manner visitors ought to receive a specific level of social and religious affectability for the length of their remain.
  • Dubai is a city and emirate in the United Arab Emirates known for extravagance shopping, ultramodern engineering and a vivacious nightlife scene. Burj Khalifa, an 830m-tall tower, commands the high rise filled horizon.
  • At its foot lies Dubai Fountain, with planes and lights choreographed to music. On manufactured islands simply seaward is Atlantis, The Palm, a resort with water and marine-creature parks.

Next Generation Sequencing Association  and Societies:

•IACSITBioinformaticsandBiomedicalEngineeringSociety(BBES)
•AfricanSocietyforBioinformaticsandComputationalBiology
•InternationalSocietyforComputationalBiology(ISCB)
•BritishSocietyforGeneticMedicine(BSGM)
•AfricanSocietyofHumanGenetics(AfSHG)
•HumanGenomeVariationSociety(HGSV)
•SocietyforMolecularBiologyandEvolution(Smbe)
•GeneticsSocietyofAmerica(GSA)
•NationalSocietyofGeneticCounselors(NSGC)
•EuropeanSocietyofHumanGenetics(ESHG)
•InternationalGeneticEpidemiologySociety(IGES)
•International Society for Animal Genetics(ISAG)

  Universities involved in Next Generation Sequencing across world:

•PurdueUniversity,USA
•StanfordUniversity,USA
•BostonUniversity,USA
•CranfieldUniversity,UK
•DeMontfortUniversity,UK
•UniversityofCalifornia,LosAngeles,USA.
•UniversityofAlberta,Canada.
•University of British Columbia, Canada.

Universities in Germany involved inNextGeneration Sequencing:

•UniversityofHamburg
•FreeUniversityBerlin
•MaxPlanckInstituteformolecularGenetics(Berlin)
•TechnischeUniversitätDresden
•FachhochschuleBingen
•TechnischeUniversitätMünchen
•JacobsUniversityBremen
•UniversityofRostock
•UniversityofTuebingen
•EuropeanMolecularBiologyLab(EMBL),Heidelberg
•DepartmentofHumanGenetics(Friedrich-Wilhelms-Universität)Bonn•Friedrich-Schiller-UniversityJena
 

Universities in Berlin involved in Next Generation Sequencing:

•FreeUniversityofBerlin
•HumboldtUniversityBerlin
•TechnicalUniversityofBerlin
•Max Planck Institute for Molecular Genetics, Berlin

Market Analysis:

•In 2014 the global market of  NGS was valued at $886.1 million and this market is expected to grow at a CAGR of  31.3 %  i.e.) from $997.1 million in 2015 to nearly $3.9 billion by 2020.

•The global  market of  NGS based cancer applications is expected to grow at a CAGR of 34.7%, from $206.3 million in 2015 to $915.7 million by 2020.

•The approach of considering  the industry is taken in terms of workflow and key indications where NGS diagnostics will have market share by 2020.

•DNA sequencing industry is segmented into instruments and consumables, services, and workflow products. Instruments and consumables segment are the rapidly emerging segments accounting for about $2.2 billion by the year 2016. Other services segment is expected to grow rapidly and reach market value of $3.5 billion with CAGR of 29% over the year 2016. The workflow segment will reach $883.6 million at CAGR of 16.6% by 2016.

•The current breakthroughs in bioinformatics, imaging, nanotechnology and microfluidics are recurring many life science fields and providing a unique platform for next generation DNA sequencing.

NGS Platforms MarketShare:

•The major players operating in the NGS market are Illumina Inc (U.S.), Thermo Fisher Scientific (U.S.), Hoffmann-La Roche Ltd (Switzerland), Pacific Bioscieces (U.S.) Agilent Technologies (U.S.), BGI (Beijing Genomics Institute) (China), Qiagen (Netherlands), Biomatters Ltd (New Zealand), and Genomatix Software GmbH (Germany).

NGS Data Analysis/Bioinformatics

Byproduct:
•NGSdataanalysissoftware
•NGSdataanalysisservices
• NGS storage management and cloud computing solutions.

Byapplication:

•WholeGenomeZequencing•ExomeSequencing
•TargetedResequencing
•DenovoSequencing
•RNA-Seq
•ChIP-Seq
•Methyl-Seq

Companies across the world for Next Generation Sequencing:

•North America is the largest market for NGS

FUNDING:

• John Templeton Foundation funded in Validation of Genomic Sequencing from the Archon X PRIZE for Genomics(AGXP)withtheamountof$720,000
•John Templeton Foundation funded in Genetics and the Origin of Organismal Complexity with the amount of $2,759,737.
• John Templeton Foundation funded in  The Genetics of High Cognitive Abilities with the amount of  $924,292
• Genome British Columbia has potential to cure 500,000 Canadian children are diagnosed with a rare disease. Now a single genomic test is capable of identifying between 6,000 and 7,000 known genetic disorders.
• Genome BC has funded 136 projects in health totaling $335 million
•In Wellcome Trust Sanger Institue the MRC and BBSRC are funding in  Mouse Genomes Project to create assembled chromosome sequences and strain-specific gene annotation for 16 strains.
•NIMH funding for the Office of Genomics Research Coordination and the DNBBS genomics portfolio.

Past Conference Report

Biostatistics 2016

We gratefully thank all our wonderful Speakers, Conference Attendees, Students, Media Partners, Associations and Sponsors for making Biostatistics 2016 Conference the best ever!

The 5rd International conference on Biometrics and Biostatistics , hosted by the ConferenceSeries was held during October 20-21, 2016 at Houston, Texas, USA based on the theme “Exploring Advances in Biometrics & Biostatistics". Benevolent response and active participation was received from the Organizing Committee Members along with Scientists, Researchers, Students and leaders from various fields of Biometrics and Biostatistics, who made this event a grand success.

ConferenceSeries expresses its gratitude to the conference Moderator, namely Azam Yazdani and Leighanne H Clavenger for taking up the responsibility to coordinate during the sessions. We are indebted to your support.

The conference was initiated with the Honorable presence of the Keynote forum. The list includes:

  • Bin Li Takeda Pharmaceuticals International Co., USA
  • Ajit Kumar Roy, Central Agricultural University, India
  • Mohammad H Rahbar, The University of Texas Health Science Center at Houston, USA
  • Mikhail Moshkov, King Abdullah University of Science and Technology, Saudi Arabia
  • Ramalingam Shanmugam, Texas State University, USA

The meeting reflected various sessions, in which discussions were held on the following major scientific tracks:

  • Clinical Biostatistics
  • Statistical Methods
  • Bayesian statistics
  • Regression Analysis
  • Bioinformatics
  • Computational Systems Biology
  • Modern data analysis
  • Biometric security
  • Adaptive biometrics systems
  • Biometrics Applications
  • Cyber security
  • Biostatistics applications

 Conference Series offers its heartfelt appreciation to organizations such as Allied Academies, Andrew John Publishing Inc., New York private Equity Forum, Crowd Reviews and other eminent personalities who supported the conference by promoting in various modes online and offline which helped the conference reach every nook and corner of the globe. Conference Series also took privilege to felicitate the Keynote Speakers, Organizing Committee Members, Chairs and sponsors who supported this event

With the grand success of Biostatistics 2016, Conference Series is proud to announce the "6th International Conference on Biostatistics and Bioinformatics" to be held during November 13-14, 2017 at Atlanta, USA.

For More details visit: http://biometrics-biostatistics.conferenceseries.com/2016

Conference Highlights

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Conference Date OCT 17-18, 2018
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